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Registro Completo |
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Biblioteca(s): |
Embrapa Pantanal. |
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Data corrente: |
25/02/2000 |
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Data da última atualização: |
31/03/2017 |
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Autoria: |
LANUSSE, C.; LIFSCHITZ, A.; VIRKEL, G.; ALVAREZ, L.; SANCHEZ, S.; SUTRA, J. F.; GALTIER, P.; ALVINERIE, M. |
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Título: |
Comparative plasma disposition kinetics of ivermectin, moxidectin and doramectin in cattle. |
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Ano de publicação: |
1997 |
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Fonte/Imprenta: |
Journal of Veterinary Pharmacology and Therapeutics, v.20, p.91-99, 1997. |
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Idioma: |
Inglês |
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Conteúdo: |
The persistance of the broad-spectrum antiparasitic activity of endectocide compounds relies on their disposition kinetics and pattern of plasma/tissues exchange in the host. This study evaluates the comparative plasma disposition kinetics of ivermectin (IVM), moxidectin (MXD) and doramectin (DRM) in cattle treated with commercially available injectable formulations. Twelve (12) parasite-free male Hereford calves (180-210 kg) grazing on pasture were allocated into three groups of four animals each. Animals in each group received either IVM (Ivomec 1%, MSD AGVET, Rahway, NJ, USA), MXI) (Cydectin 1%, American Cyanamid, Wayne, NJ, USA) or DRM (Dectomax 1%, Pfizer Inc., New York, USA) by subcutaneous injection at a dose of 200 ug/kg. Jugular blood samples were collected from 1 h to 80 days post-treatment, and plasma extracted, derivated and analysed by high performance liquid chromatography (HPLC) using fluorescence detection. |
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Thesagro: |
Gado; Plasma; Sanidade Animal. |
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Thesaurus Nal: |
cattle; doramectin; ivermectin; moxidectin. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 01702naa a2200289 a 4500
001 1799785
005 2017-03-31
008 1997 bl --- 0-- u #d
100 1 $aLANUSSE, C.
245 $aComparative plasma disposition kinetics of ivermectin, moxidectin and doramectin in cattle.
260 $c1997
520 $aThe persistance of the broad-spectrum antiparasitic activity of endectocide compounds relies on their disposition kinetics and pattern of plasma/tissues exchange in the host. This study evaluates the comparative plasma disposition kinetics of ivermectin (IVM), moxidectin (MXD) and doramectin (DRM) in cattle treated with commercially available injectable formulations. Twelve (12) parasite-free male Hereford calves (180-210 kg) grazing on pasture were allocated into three groups of four animals each. Animals in each group received either IVM (Ivomec 1%, MSD AGVET, Rahway, NJ, USA), MXI) (Cydectin 1%, American Cyanamid, Wayne, NJ, USA) or DRM (Dectomax 1%, Pfizer Inc., New York, USA) by subcutaneous injection at a dose of 200 ug/kg. Jugular blood samples were collected from 1 h to 80 days post-treatment, and plasma extracted, derivated and analysed by high performance liquid chromatography (HPLC) using fluorescence detection.
650 $acattle
650 $adoramectin
650 $aivermectin
650 $amoxidectin
650 $aGado
650 $aPlasma
650 $aSanidade Animal
700 1 $aLIFSCHITZ, A.
700 1 $aVIRKEL, G.
700 1 $aALVAREZ, L.
700 1 $aSANCHEZ, S.
700 1 $aSUTRA, J. F.
700 1 $aGALTIER, P.
700 1 $aALVINERIE, M.
773 $tJournal of Veterinary Pharmacology and Therapeutics$gv.20, p.91-99, 1997.
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Registro original: |
Embrapa Pantanal (CPAP) |
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